| 1st Qualifying Round | 2nd Qualifying Round | 3rd Qualifying Round | Play-offs | Group Stage | Round of 16 |
| Quarterfinals | Semifinals | Final |
Rodada:
Jogados
2ª Rodada
29/09/2021 - Quarta
15:00
Red Bull Salzburg
2
x
1
Lille
15:00
Wolfsburg
1
x
1
Sevilla
3ª Rodada
19/10/2021 - Terça
12:45
Beşiktaş
1
x
4
Sporting CP
12:45
Club Brugge
1
x
5
Manchester City
15:00
Ajax
4
x
0
Borussia Dortmund
15:00
Atlético de Madrid
2
x
3
Liverpool
15:00
Internazionale
3
x
1
Sheriff
15:00
Paris Saint-Germain
3
x
2
RB Leipzig
15:00
Porto
1
x
0
Milan
15:00
Shakhtar Donetsk
0
x
5
Real Madrid
20/10/2021 - Quarta
12:45
Barcelona
1
x
0
Dynamo Kyiv
12:45
Red Bull Salzburg
3
x
1
Wolfsburg
15:00
Benfica
0
x
4
Bayern Munich
15:00
Chelsea
4
x
0
Malmö
15:00
Lille
0
x
0
Sevilla
15:00
Manchester United
3
x
2
Atalanta
15:00
Young Boys
1
x
4
Villarreal
15:00
Zenit
0
x
1
Juventus
4ª Rodada
02/11/2021 - Terça
13:45
Malmö
0
x
1
Chelsea
13:45
Wolfsburg
2
x
1
Red Bull Salzburg
16:00
Atalanta
2
x
2
Manchester United
16:00
Bayern Munich
5
x
2
Benfica
16:00
Dynamo Kyiv
0
x
1
Barcelona
16:00
Juventus
4
x
2
Zenit
16:00
Sevilla
1
x
2
Lille
16:00
Villarreal
2
x
0
Young Boys
03/11/2021 - Quarta
13:45
Milan
1
x
1
Porto
13:45
Real Madrid
2
x
1
Shakhtar Donetsk
16:00
Borussia Dortmund
1
x
3
Ajax
16:00
Liverpool
2
x
0
Atlético de Madrid