| 1st Qualifying Round | 2nd Qualifying Round | 3rd Qualifying Round | Play-offs | Group Stage | Round of 16 |
| Quarterfinals | Semifinals | Final |
Rodada:
Jogados
4ª Rodada
03/11/2021 - Quarta
16:00
Manchester City
4
x
1
Club Brugge
16:00
RB Leipzig
2
x
2
Paris Saint-Germain
16:00
Sheriff
1
x
3
Internazionale
16:00
Sporting CP
4
x
0
Beşiktaş
5ª Rodada
23/11/2021 - Terça
12:45
Dynamo Kyiv
1
x
2
Bayern Munich
12:45
Villarreal
0
x
2
Manchester United
15:00
Barcelona
0
x
0
Benfica
15:00
Chelsea
4
x
0
Juventus
15:00
Lille
1
x
0
Red Bull Salzburg
15:00
Malmö
1
x
1
Zenit
15:00
Sevilla
2
x
0
Wolfsburg
15:00
Young Boys
3
x
3
Atalanta
24/11/2021 - Quarta
12:45
Beşiktaş
1
x
2
Ajax
12:45
Internazionale
2
x
0
Shakhtar Donetsk
15:00
Atlético de Madrid
0
x
1
Milan
15:00
Club Brugge
0
x
5
RB Leipzig
15:00
Liverpool
2
x
0
Porto
15:00
Manchester City
2
x
1
Paris Saint-Germain
15:00
Sheriff
0
x
3
Real Madrid
15:00
Sporting CP
3
x
1
Borussia Dortmund
6ª Rodada
07/12/2021 - Terça
12:45
Paris Saint-Germain
4
x
1
Club Brugge
12:45
RB Leipzig
2
x
1
Manchester City
15:00
Ajax
4
x
2
Sporting CP
15:00
Borussia Dortmund
5
x
0
Beşiktaş
15:00
Milan
1
x
2
Liverpool
15:00
Porto
1
x
3
Atlético de Madrid
15:00
Real Madrid
2
x
0
Internazionale
15:00
Shakhtar Donetsk
1
x
1
Sheriff
08/12/2021 - Quarta
12:45
Juventus
1
x
0
Malmö
12:45
Zenit
3
x
3
Chelsea